People holding undergraduate degrees, working in other sectors rather than healthcare, and having definite-term contract had a higher likelihood of income reduction. Results showed that among 341 participants, 66.9% reported household income loss due to the impact of COVID-19. Ordered logistic regression and multivariable Tobit regression model were employed to examine factors correlated to income change and HRQOL. The data included socio-economic characteristics, impact of COVID-19 on household income, health status, and health-related quality of life (HRQOL). A cross-sectional study using a web-based approach was conducted in the second week of April 2020 to examine the influence of the national social distancing on the quality of life and economic well-being of Vietnamese citizens under COVID-19 pandemic. Starting from April 1st, 2020, the nationwide partial lockdown in Vietnam has shown the effectiveness in stopping the community transmission of COVID-19, however, it also produced adverse impacts on the economy and inhabitants’ life. 8Institute for Health Innovation and Technology (iHealthtech), National University of Singapore, Singapore, Singapore.7Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.6Department of Psychological Medicine, National University Hospital, Singapore, Singapore.5Center of Excellence in Evidence-based Medicine, Nguyen Tat Thanh University, Ho Chi Minh City, Vietnam.4Faculty of Medicine, Duy Tan University, Da Nang, Vietnam.3Institute for Global Health Innovations, Duy Tan University, Da Nang, Vietnam.2Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States.1Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam.Latkin 2, Hai Quang Pham 3,4, Linh Gia Vu 5, Xuan Thi Thanh Le 1, Thao Thanh Nguyen 1, Quan Thi Pham 1, Nhung Thi Kim Ta 1, Quynh Thi Nguyen 1, Cyrus S. Bach Xuan Tran 1,2*, Hien Thi Nguyen 3,4, Huong Thi Le 1, Carl A.
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